Mo et al. (2014) performed a predictive search of miRNAs targeting IFITM5 in human osteosarcoma (ORPHA:668) cell lines using DIANA-microT, a tool based on the microT algorithm, which is particularly trained on a positive and a negative set of miRNA recognition elements (MREs) located in both the 3′-UTR and CDS regions. The authors identified miR-762 as a novel regulator of IFITM5, shedding new light on the roles of miRNAs in osteoblast differentiation (Mo et al., 2014). The gene discussed is IFITM5; the disease is osteosarcoma.