Because an increased expression of TLR4 in CRC is common and TLR4/MyD88 signaling is associated with poor prognosis (Wang et al., 2010; Kantola et al., 2012; Tye and Jenkins, 2013), we analyzed TLR4 expression in colorectal adenocarcinoma specimen according to MMR status. This evidence concerns the gene TLR4 and colorectal carcinoma.