Five patients had IDH1-mutant grade 3 gliomas, three patients had an integrated histological and molecular diagnosis of glioblastoma multiforme, ten had grade 2 gliomas, one had brain metastases from a non-small cell lung carcinoma, one had a diagnosis of radiation necrosis and one had a central nervous system lymphoma. The gene discussed is IDH1; the disease is non-small cell lung carcinoma.