MRPL15 and non-small cell lung carcinoma: Due to human leukocyte antigen (HLA) holding a predictive role in developing immune-related adverse events (irAEs) during therapy in NSCLC (45), we also investigated significantly lower expression level of the human leukocyte antigen (HLA) family genes in high-expression MRPL15 group in LUAD and LUSD (Supplementary Figures 4A, B).