On average, the risk of cancer differs between the two genes, as for BRCA1 the assessed average risk of breast and ovarian cancers ranges from 57 to 65% and from 20 to 50%, respectively, and for BRCA2 the risk ranges from 35 to 57% and from 5 to 23%, respectively (9, 10). The gene discussed is BRCA2; the disease is cancer.