YTHDF1 and rectum adenocarcinoma: For different molecular subtypes of cancers, a significant connection with YTHDF1 expression existed in BRCA, COAD, ESCA, HNSC, KIRP, LGG, LUSC, OV, PCPG (Pheochromocytoma and Paraganglioma), READ (rectum adenocarcinoma), STAD and UCEC (Figure 4).