XXYLT1 and non-small cell lung carcinoma: Western blot analysis indicated that C3orf21 expression varied in the different NSCLC cell lines (Figure 4A) and treatment with beta-elemene (10 μg/ml) for 24 h significantly up-regulated C3orf21 expression in these NSCLC cells (p < 0.05—p < 0.001, Figure 4B).