CTBP1 and neoplasm: Another report well documented that depletion of CtBP1 resulted in small and slow growth of tumor in an androgen-independent model (e.g., PC-3 xenografts model) [267]; therefore, it can be suggested that CtBP-1 plays a significant role in the modulation of hormones within the tumor by helping of transcriptional factors and leads to the development of high dietary intakes of lipids induced carcinogenesis in the prostate.