These islets are individual organoids mainly composed of a majority of β‐cells (≈80% of total cells), usually locate within the islet core area, α‐cells (≈10% of total cells) and some other islet cells towards the outer islet region.[21] During T1D progression however, immune cells would attack the insulin‐producing β‐cells, a process that destroys islet β‐cells and its insulin producing ability. The gene discussed is INS; the disease is type 1 diabetes mellitus.