stated that Gram‐positive commensal bacteria‐mediated antigen presentation on CD11b+ DCs, and the depletion of these bacteria through oral administration of vancomycin promoted major histocompatibility complex (MHC) I‐dependent activation of anti‐tumor CD8+ T cells, thus improving the therapeutic outcomes of radiotherapy on tumor‐bearing mice.[77]Bifidobacterium bifidum acts as a potent inducer of CD25+ Foxp3+ Tregs, in a regulatory DCs (MHC II+ CD11c+ CD11b+ CD103+ colonic lamina propria DCs) TLR2‐dependent manner. The gene discussed is TLR2; the disease is neoplasm.