CD4 and Autoimmunity: Dramatic differences were observed, e.g., for gas plasma‐treated Ova oxidation/dioxidation/trioxidation in amino acids across the entire protein – types of modifications, a recent autoimmunity ligandomic study, for instance, excluded explicitly in its mass spectrometry peptide analysis workflow.[124] We found these types of oxidations to align in the Ova323‐339 (CD4+) but not the Ova257‐264 (CD8+) peptide‐binding region, apart from other oxidation hot spots located at three distinct hyperoxidized regions of Ova.