In cancer metastasis, several signaling pathways, including hypoxia, Wnt, Notch, Hedgehog, and TGFβ, play vital roles in EMT.[46, 47, 48, 49, 50] Therefore, we explored whether CUL4B is functionally associated with these breast cancer EMT‐associated signaling pathways, which were also enriched in our CUL4B ChIP‐seq experiments. Here, CUL4B is linked to breast carcinoma.