Among the key genes, C1ORF105 was associated with a larger inter-adventitial common carotid artery diameter (ICCAD) (Harrison et al., 2013), and FAM132b can be increased by induction of erythrogenesis (Gurieva et al., 2017), suggesting that they may play an important role in the occurrence and development of cancer. Here, C1orf105 is linked to cancer.