Godoy et al. (2014) found that the high expression of GBP2 was associated with a better prognosis in breast cancer, which may be due to the fact that GBP2 represents an effective marker of the T cell response. GBP2 can prevent the translocation of dynamin-related protein 1 (Drp1) from the cytoplasm to the mitochondria, thus weakening the Drp1-dependent mitochondrial fission and the invasion of breast cancer cells (Zhang et al., 2017). The gene discussed is GBP2; the disease is breast cancer.