KEAP1 and non-small cell lung carcinoma: Genistein mediated selective radiosensitizing effects in non-small cell lung cancer (NSCLC) A549 cells by inhibiting the methylation of the Keap1 gene promoter region; hypermethylation of the Keap1 promoter results in chemo/radioresistance mediated by the Nrf2-Keap1 pathway [83].