The Met174 allele of AGT p.Thr174Met might increase the plasma levels of AGT and Ang II, thereby increasing vasoconstriction, VSMC proliferation, and lipid deposition; this allele participates in the pathogenesis of atherosclerosis, hypertension, and MI and increases the MI risk [11, 13–15]. The gene discussed is AGT; the disease is atherosclerosis.