Additional dmCpG in regulatory regions of pathobiologically relevant genes included PA-dmCpG within the ACBD5 that is involved in long-chain FA metabolism (Ferdinandusse et al., 2017); CD34, an adipocyte progenitor marker (Hui et al., 2007); and CDH18 that hosts variants associated with the metabolic syndrome (Zhang et al., 2013). The gene discussed is ACBD5; the disease is metabolic syndrome.