Finally, 22 variables were significantly associated with D-dimer: respiratory rate, systolic pressure, dyspnea, serum K+, neutrophils, globulin, CRP, ferritin, LDH, PCT, SpO2, blood glucose, BUN, total bilirubin, ALT, AST, CK, mortality, ventilation, ARDS, sepsis, and acute cardiac injury (Figure 4). This evidence concerns the gene CRP and acute respiratory distress syndrome.