2) Interestingly, Mice bearing MC38 tumor cells treated with CXCR2-transduced pmel-1 T cells showed enhanced tumor regression and survival compared with mice receiving control, which implicated that the introduction of the CXCR2 gene into tumor-specific T cells could enhance their localization to tumors and improve antitumor immune responses, and it was correlated our results with CXCR2 mediated DC to suppression role in tumor growth (34). Here, CXCR2 is linked to neoplasm.