About disease presentation, in the MOG-IgG+ group the majority of patients (65.9%) presented with ON, 14.7% had myelitis, 2.4% had both ON and myelitis, 7.3% were clinically diagnosed with seronegative NMOSD, 7.3% had ADEM, and 2.4% had epileptic seizures. The gene discussed is MOG; the disease is acute disseminated encephalomyelitis.