In humans, LAG-3 is expressed on CD8+ tumor-infiltrating lymphocytes (TILs) and peripheral Tregs (Camisaschi et al., 2010; Matsuzaki et al., 2010; Li et al., 2013; Llosa et al., 2015; Taube et al., 2015). The gene discussed is LAG3; the disease is neoplasm.