CASP3 and cancer: Resveratrol has also been demonstrated to possess beneficial effects (Moni et al., 2018) it promotes apoptosis via ROS-dependent caspase activation (Shankar et al., 2007) and Bax/caspase-3 (Whitlock and Baek, 2012) and induces apoptosis associated with mitochondrial dysfunction in cancer cells (Lin et al., 2012).