EGFR and neoplasm: To validate the role of EGFR in AcoA-induced toxicity, we compared the GI50 (concentrations of 50% growth inhibition) data of AcoA in the NCI-60 human tumor cell lines available from the database of the United States National Cancer Institute (NCI) to EGFR log2 relative protein expression data from the same database (https://dtp.cancer.gov/discovery_development/nci-60/).