C9 and amyotrophic lateral sclerosis: This is in contradiction to the observed decrease in V1 transcript and bears no explanation so far, but it must be reminded that only three C9-ALS cases could be examined in that study and that the abundance of C9-short is generally admitted to be very low (Waite et al., 2014; Frick et al., 2018; Saberi et al., 2018).