DPYSL2 and schizophrenia: For example, polymorphisms in the genes encoding CRMP1 and CRMP2, as well as altered hippocampal expression of CRMP2 and CRMP4 have been reported in patients with schizophrenia (Edgar et al., 2000; Beasley et al., 2006; Föcking et al., 2011; Bader et al., 2012).