FLT3 and acute myeloid leukemia: To determine whether combined treatment with a FLT3 TKI and a BCL-2 inhibitor would increase the inhibition of cell proliferation of FLT3/ITD cells, we carried out the MTT assay on Molm14 and MV4;11 cell lines, both of which were derived from AML patients with FLT3/ITD mutations.