Four abnormal tests at baseline were associated with significance odds of ICU admission: leukocytocis (4.45, 95%CI: 1.49, 13.31), lymphopenia (2.39, 95%CI: 1.30, 4.39), increased CPK (1.99, 95%CI: 1.04-3.83), and increased AST (2.25, 95%CI: 1.18, 4.30). The gene discussed is PIK3C2A; the disease is lymphopenia.