In prostate cancer, the overexpression of LINC00261 was shown to inhibit the transcription of dickkopf-related protein 3 (DKK3) by recruiting GATA binding protein 6 (GATA6), resulting in the inhibition of tumor angiogenesis; this action was reversed by silencing DKK3. The gene discussed is DKK3; the disease is Familial prostate cancer.