The Abelson (ABL) family of tyrosine kinases ABL1 (c-ABL) and ABL2 (ABL-related gene, ARG) regulate diverse cellular processes during development and normal homeostasis, but ABL kinases are aberrantly activated during tumor progression, metastasis, tissue injury responses, inflammation, neural degeneration and other diseases [2–11]. Here, ABL2 is linked to neoplasm.