We found that BMI, WC, HOMA-IR, TG, SUA, TT, FT, 25(OH)D3, and E2 were positively correlated with hypogonadism (r = 0.556, 0.139, 0.473, 0.143, 0.134, 0.462, 0.419, 0.572, 0.601,P = 0.012, 0.027, 0.018, 0.019, 0.028, 0.029, 0.030, 0.009, 0.003, respectively), and FPG, FINS, ALT were not associated with hypogonadism (r = 1.101, 1.321, 1.231, P = 0.622, 0.691,0.673, respectively). This evidence concerns the gene GPT and hypogonadism.