In patients with normoalbuminuric T2DM, compared with the control group (non-DKD), NADKD was significantly associated with older age; female sex; higher prevalence and longer duration of diagnosed hypertension; higher PP, higher SUA; higher use of insulin before hospital admission; higher prevalence of anemia; higher prior use of antihypertensive drugs and lipid-lowering drugs; higher prior use of RASIs; and lower levels of DBP, HbA1c, TC, ApoB, and ApoB/ApoAI. The gene discussed is INS; the disease is hypertensive disorder.