INS and obesity due to melanocortin 4 receptor deficiency: In our previous patient series report of 94 patients with obesity and T2D with preserved pancreatic function, namely with a relatively short T2D disease duration before surgery, reasonable pre-operative glycemic control as assessed by HbA1C levels and small proportion of patients requiring insulin therapy for disease control, RYGB with 200 cm biliopancreatic limb resulted in a diabetes remission rate of 87.91% at 6 months, 92.68% at 12 months, 92.85% at 24 months, and 100% at 36 months of follow-up [26].