In addition, chit1, Ifng and Lat2, which are involved in the immune response and Bcl3, Bop1, Fanca, Gpr161, P2ry1, Slc22a20, Sva, Yif1b and Zc3h12a, which are involved in the maintenance of pluripotency, the cell cycle, DNA repair, tumour suppression, mitochondrial metabolism, germ cell proliferation, calcium oscillation, the organization of the Golgi architecture, and maintenance of endothelial homeostasis, were also upregulated. The gene discussed is GPR161; the disease is neoplasm.