HK1 and cancer: We first found that YTHDC1 mRNA expression was downregulated in cancer tissues compared with nontumor tissues (Fig. 6b), and there was a positive association between YTHDC1 and miR-30d (Supplementary Fig. 6c) and a negative association between YTHDC1 and RUNX1, SLC2A1, HK1 (Supplementary Fig. 6d).