In the published data first used to establish the subtypes within the 4 medulloblastoma subgroups2, SHH-subgroup tumors showed significantly higher HLA-DRA mRNA (Fig. 7f), and SHH-alpha subtype tumors showed significantly lower HLA-DRA mRNA, compared to the other SHH subtypes (Fig. 7g). Here, HLA-DRA is linked to medulloblastoma.