ATP5MK and schizophrenia: Since ATP5MD mRNA expression was observed to be downregulated in schizophrenia (Supplementary Fig. 4), we therefore employed shRNA to directly knockdown (KD) the endogenous ATP5MD expression, and observed that ATP5MD-KD significantly attenuated neural development, yielding a decreased soma size and neurite length of 2-week-old human iPSC-derived cortical neurons (one-way ANOVA P < 1e-4.