SC5D and early-onset non-syndromic cataract: Additionally, lathosterolosis and microcephaly, congenital cataract, and psoriasiform dermatitis (MCCPD), caused by deficiency in either sterol-C5-desaturase (SC5D) or methylsterol monoxygenase 1 (MSMO1), is known to display cataracts as one of the clinical features27,28.