Finally, we examined EU labelling in the cerebellum of two Purkinje cell-specific mutant mouse models for, respectively, a severe progeroid DNA repair deficiency syndrome (Ercc1d/fPcp2-Cre mice) [11] and spinocerebellar ataxia 1 (SCA1, ATXN1[82Q] mice) [7]. Here, ATXN1 is linked to spinocerebellar ataxia type 1.