MGMT and glioblastoma: GBM is incurable with a progression‐free survival (PFS) of 7–8 months and a median overall survival (OS) of 16–22 months depending on prognostic and predictive markers [11, 12, 13, 14], including isocitrate dehydrogenase (IDH) status, O6‐methylguanine‐DNA methyltransferase (MGMT) promoter methylation status, performance status (PS), use of corticosteroids, and extent of surgery.