INS and obesity due to melanocortin 4 receptor deficiency: To begin to understand if the altered adipocyte metabolism observed in LMO3-expressing adipocytes in vitro may also be associated with an “healthier” AT in obesity, we re-analyzed a previously published microarray dataset of WAT derived from morbidly obese patients grouped into “metabolically healthy” or “metabolically unhealthy” obesity (MHO vs. MUO) based on the degrees of insulin sensitivity [42].