The circRNA–miRNA–gene regulatory networks have largely found in previous exploration of circRNAs in glioma, such as circ_0074362/miR-1236-3p/HOXB7 [35], circMAN2B2/miR-1205/SA00A8 [36] and circ_0088732/miR-661/RAB3D [37]. Here, HOXB7 is linked to central nervous system cancer.