FOXO3 and hepatocellular carcinoma: For instance, it has been reported that miR-153 (24) and miR-20a (25) enhanced oxaliplatin resistance by inhibiting FOXO3a and BNIP2 in colorectal cancer, whereas miR-122 (26, 27) sensitizes hepatocellular carcinoma to oxaliplatin by inhibiting the Wnt/β-catenin pathway.