PPIAP22 and colon adenocarcinoma: Kouyama et al. (2019) reported DDX56 regulated COAD cell proliferation and cell cycle both in vitro and in vivo by promoting WEE1. Pathway and GO enrichment analysis revealed that the top 100 related genes of CCT6A were mainly related to ribosome biogenesis and mismatch repair (Figures 8A–D). We also found that several genes such as MPLKIP and PPIAP22 in this network were significantly associating with COAD patients’ survival (Figures 8F,G).