GSK3B and acute respiratory distress syndrome: In addition, mice subjected to systemic administration of adenoviral vector expressing vaspin were protected against LPS-induced acute respiratory distress syndrome by alleviating the pulmonary inflammatory response and pulmonary endothelial barrier dysfunction, which was accompanied by activation of the Akt/GSK3β pathway, leading to the phospho-inactivation of GSK3β (70) (Table S1).