HLA-DRB1 and toxic epidermal necrolysis: We also observed a significant association of HLA-DRB1*15:01, HLA-B*13:01–C*03:04, and HLA-B*13:01–DRB1*15:01 with dapsone-induced SJS-TEN when compared with tolerant controls and general Thai population (p < 0.05).