As we previously discussed (24), only three mouse models for indolent lymphomas of the spleen have been published, one mimicking TRAF3 inactivation, the second with constitutive expression of BCL10 and the last one with continuous CD40 signaling (the L.CD40 model that we used as a control in Figure 7) (28, 49, 50). This evidence concerns the gene TRAF3 and lymphoma.