MYD88 and diffuse large B-cell lymphoma: Indeed, MYD88 mutations are also found in 30% of activated B-cell type diffuse large B-cell lymphomas (ABC-DLBCL), more than half of primary cutaneous DLBCLs, leg type, and many DLBCLs at immune-privileged sites but not in plasma cell myelomas, even IgM types (9).