NOS2 and brain ischemia: In the acute stage of cerebral ischemia, borneol improves cerebral blood flow by relaxing blood vessels and eliciting anti-thrombotic effects, inhibits neuronal excitotoxicity by reducing Glu levels and activating GABAA receptors, improves the ability of the body to resist ROS injury by increasing the activity of antioxidant enzymes, regulates the activity of different types of NOS and antagonizes the neurotoxic effect of NO, reduces the content of intracellular Ca2+, interferes with the process of neuron death, and antagonizes the symptoms of acutely elevated body temperature.