BRD4 and acute myeloid leukemia: SEs/Es of myeloid lineage transcription factors (TFs) and of their target genes in AML LSCs are characterized by histone H3 lysine (K) 27 acetyl (H3K27Ac) and H3K4 mono-methylation (H3K4Me1) marks, as well as by high occupancy with BRD4 and histone acetyl transferase CBP/p3007–9.