Also, in patients with lung adenocarcinoma, a high proportional expression of Fas in the naïve CD8+ T lymphocytes was observed, which could result in specific apoptosis of CD8+ T preferential apoptosis expressing Fas when they arrived the stage of efficacy by FasL being expressed, such as immune cells, tumor cells, or other cells might cause apoptosis [29]. The gene discussed is CD8A; the disease is neoplasm.