On average women mount stronger and more structured immune-response against NSCLC, as highlighted by the higher intratumor abundance of plasmacytoid and activated dendritic cells, CD4+ and CD8+ effector T-cells, memory CD4+ T-cells and B-cells including Class-switched memory cells, as well as by greater clonality of the TCR-repertoire.33,34,36. Here, CD8A is linked to non-small cell lung carcinoma.